SCHEMBL95345

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10422318	0.86	SLC25A1 (0.66)	ALDH1A1MAPTPOLBTDP1NHERF1
	SCHEMBL95317	0.84	SMN1; SMN2 (0.60)	ALDH1A1MAPTTDP1MEN1KMT2A
	SCHEMBL9635088	0.82	ALDH1A1 (0.53)	ALDH1A1MAPTPOLBTDP1NHERF1
	SCHEMBL95927	0.80	ALDH1A1 (0.67)	ALDH1A1MAPTTDP1MCL1MEN1
	SCHEMBL98037	0.78	CA2 (0.71)	ALDH1A1MAPTTDP1MEN1KMT2A
	SCHEMBL1471788	0.77	MCL1 (0.59)	ALDH1A1MAPTPOLBNHERF1MCL1
	SCHEMBL5172845	0.77	NHERF1 (0.58)	ALDH1A1MAPTTDP1NHERF1MCL1
	SCHEMBL23832701	0.77	IDH1 (0.54)	ALDH1A1MAPTPOLBNHERF1MCL1
	SCHEMBL30218156	0.77	IDH1 (0.54)	ALDH1A1MAPTPOLBNHERF1MCL1
	SCHEMBL7580547	0.76	IDH1 (0.71)	NHERF1MCL1SMN1; SMN2IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.