Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | GALR3 | O60755 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27968084 | 1.00 | TLR8 (0.56) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL27968081 | 1.00 | TLR8 (0.56) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL27968082 | 1.00 | TLR8 (0.56) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL11669837 | 1.00 | TLR8 (0.56) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL28813838 | 1.00 | TLR8 (0.56) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL5655364 | 0.98 | TLR8 (0.57) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL5657514 | 0.93 | ALDH1A1 (0.58) | TLR8POLBALDH1A1KMT2AHTT | |
| SCHEMBL1206348 | 0.86 | ALDH1A1 (0.43) | TLR8POLBALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28278332 | 0.83 | TLR8 (0.56) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL3419618 | 0.83 | TLR8 (0.56) | TLR8POLBALDH1A1KMT2ATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114699391-A | Rotigting transdermal absorption patch | 北京福元医药股份有限公司 | 2022-07-05 | — | — | CN | claimed |
| CN-113813370-A | Medicine for ankylosing spondylitis and preparation method thereof | 上海强直医院有限公司 | 2021-12-21 | — | — | CN | claimed |
| CN-107669661-B | Diclofenac sodium transdermal patch | 山东朱氏药业集团有限公司 | 2020-05-26 | — | — | CN | claimed |
| CN-116178362-B | Aggregation-induced emission material based on benzothiazole hydrazone, and preparation method and application thereof | 河南农业大学 | 2025-03-04 | — | — | CN | disclosed |
| CN-116178362-A | Aggregation-induced emission material based on benzothiazole hydrazone, and preparation method and application thereof | 河南农业大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-114699391-A | Rotigting transdermal absorption patch | 北京福元医药股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-114699391-A | Rotigting transdermal absorption patch | 北京福元医药股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-113813370-A | Medicine for ankylosing spondylitis and preparation method thereof | 上海强直医院有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-113813370-A | Medicine for ankylosing spondylitis and preparation method thereof | 上海强直医院有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-107669661-B | Diclofenac sodium transdermal patch | 山东朱氏药业集团有限公司 | 2020-05-26 | — | — | CN | disclosed |
| CN-103951620-A | Synthetic method of 1-alkyl-1 H-imidazole-2-formaldehyde | UNIV JIANGNAN | 2014-07-30 | — | — | CN | disclosed |
| US-20140171431-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2014-06-19 | — | — | US | disclosed |
| US-20140171431-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2014-06-19 | — | — | US | disclosed |
| EP-2725024-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2014-04-30 | — | — | EP | disclosed |
| EP-2725024-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2014-04-30 | — | — | EP | disclosed |
| WO-2013000108-A1 | AZOLE HETEROCYLIC COMPOUNDS, PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 中国科学院上海药物研究所 (CN) | 2013-01-03 | — | — | WO | disclosed |
| WO-2013000267-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 中国科学院上海药物研究所 (CN) | 2013-01-03 | — | — | WO | disclosed |
| EP-0528957-A4 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0528957-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-03 | — | — | EP | disclosed |
| WO-1991016889-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171431-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | PLA2G5, LTA4H, PLA2G4A | TLR8 2086/4885POLB 3703/4885ALDH1A1 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.