SCHEMBL1206348

SCHEMBL1206348

CCCn1ccnc1C=O

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.43
TLR8 Q9NR97 2/20 0.41
PDE4A P27815 4/20 0.38
PDE4B Q07343 4/20 0.38
PDE4C Q08493 4/20 0.38
PDE4D Q08499 4/20 0.38
PDE1A P54750 2/20 0.38
PDE1B Q01064 2/20 0.38
PDE1C Q14123 2/20 0.38
MEN1 O00255 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5657514 0.89 ALDH1A1 (0.58) ALDH1A1KMT2APOLBTLR8PDE4A
SCHEMBL5655364 0.87 TLR8 (0.57) ALDH1A1KMT2APOLBTLR8SMN1; SMN2
SCHEMBL27968082 0.86 TLR8 (0.56) ALDH1A1KMT2APOLBTLR8SMN1; SMN2
SCHEMBL11669837 0.86 TLR8 (0.56) ALDH1A1KMT2APOLBTLR8SMN1; SMN2
SCHEMBL27968081 0.86 TLR8 (0.56) ALDH1A1KMT2APOLBTLR8SMN1; SMN2
SCHEMBL28813838 0.86 TLR8 (0.56) ALDH1A1KMT2APOLBTLR8SMN1; SMN2
SCHEMBL9535005 0.86 TLR8 (0.56) ALDH1A1KMT2APOLBTLR8SMN1; SMN2
SCHEMBL27968084 0.86 TLR8 (0.56) ALDH1A1KMT2APOLBTLR8SMN1; SMN2
SCHEMBL1206354 0.84
SCHEMBL2497098 0.81 ADORA2A (0.37) ALDH1A1KMT2APOLBTLR8PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114768545-B Nitrocellulose microporous membrane and continuous preparation method thereof 青岛吉景新型材料有限公司 2023-11-10 CN claimed
CN-114768545-A Cellulose nitrate microporous membrane and continuous preparation method thereof 青岛吉景新型材料有限公司 2022-07-22 CN claimed
CN-121748449-B Imidazole high-temperature proton exchange membrane with twisted structure and preparation method thereof 东北大学 2026-04-28 CN disclosed
CN-121748449-A Imidazole high-temperature proton exchange membrane with twisted structure and preparation method thereof 东北大学 2026-03-27 CN disclosed
US-12545668-B2 Cyclic amine derivative as agent for promoting advillin function, and novel cyclic amine derivative and pharmaceutical use thereof TORAY INDUSTRIES, INC. (JP) 2026-02-10 US disclosed
EP-3777858-B1 AGENT FOR INHIBITING RISE IN INTRANEURONAL CALCIUM CONCENTRATION TORAY INDUSTRIES (JP) 2025-04-02 EP disclosed
CN-111902143-B Inhibitors of calcium concentration increase in nerve cells 东丽株式会社 2024-01-02 CN disclosed
CN-117285516-A Dehydrogenated phenyl achyranthis statin compound, preparation method and application thereof 大连万众益生大健康有限公司 2023-12-26 CN disclosed
CN-114768545-B Nitrocellulose microporous membrane and continuous preparation method thereof 青岛吉景新型材料有限公司 2023-11-10 CN disclosed
US-11510914-B2 Agent for inhibiting rise in intraneuronal calcium concentration TORAY INDUSTRIES, INC. (JP) 2022-11-29 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
WO-2010017055-A2 DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) LEAD THERAPEUTICS, INC. (US) 2010-02-11 WO disclosed
US-20100035883-A1 DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) LEAD THERAPEUTICS, INC. (US) 2010-02-11 US disclosed
US-20070208033-A1 For use as antimetastatic agent or antiviral agent for HIV infection; N-(4-dipropylaminomethylphenyl)-4-{[(1H-imidazol-2-ylmethyl)-(1-methyl-1H-imidazol-2-ylmethyl)-amino]-methyl}-benzamide; chemokine receptor CXCR4 antagonists KUREHA CORPORATION (JP) 2007-09-06 US disclosed
US-7262185-B2 Benzazepine derivative, process for producing the same, and use TAKEDA CHEMICAL INDUSTRIES LTD. (JP) 2007-08-28 US disclosed
US-7176227-B2 For example, N-(4-{[bis(1H-imidazol-2-ylmethyl)-amino]-methyl}-benzyl)-N',N'-dipropylbutane-1,4-diamine; efficacious against diseases such as infection with HIV virus, rheumatism, and cancer metastasis KUREHA CORPORATION (JP) 2007-02-13 US disclosed
US-20050165063-A1 Amine compounds and use thereof KUREHA CHEMICAL INDUSTRY COMPANY, LIMITED. (JP) 2005-07-28 US disclosed
EP-1550657-A1 AMINE COMPOUNDS AND USE THEREOF Kureha Chemical Industry Co., Ltd. (JP) 2005-07-06 EP disclosed
US-20040235822-A1 Benzazepine derivative, process for producing the same, and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-11-25 US disclosed
EP-1422228-A1 BENZAZEPINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Chemical Industries, Ltd. (JP) 2004-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545668-B2 Cyclic amine derivative as agent for promoting advillin function, and novel cyclic amine derivative and pharmaceutical use thereof SSB, TLR9, C5AR2 ALDH1A1 2744/4885KMT2A 2657/4885POLB 1826/4885
US-11510914-B2 Agent for inhibiting rise in intraneuronal calcium concentration ITPR2, ATP2A2, ORAI1 ALDH1A1 4246/4885KMT2A 4251/4885POLB 3695/4885
US-20050165063-A1 Amine compounds and use thereof NR0B2, NR5A2, NR1H4 ALDH1A1 1505/4885KMT2A 721/4885POLB 2647/4885
US-20100035883-A1 DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) PARP1, PARP2, PARP11 ALDH1A1 326/4885KMT2A 1270/4885POLB 19/4885
US-20040235822-A1 Benzazepine derivative, process for producing the same, and use CYP1B1, CYP1A1, CYP2E1 ALDH1A1 519/4885KMT2A 391/4885POLB 3578/4885
US-20070208033-A1 For use as antimetastatic agent or antiviral agent for HIV infection; N-(4-dipropylaminomethylphenyl)-4-{[(1H-imidazol-2-ylmethyl)-(1-methyl-1H-imidazol-2-ylmethyl)-amino]-methyl}-benzamide; chemokine receptor CXCR4 antagonists CXCR4, CXCR6, CCR5 ALDH1A1 1689/4885KMT2A 617/4885POLB 3667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.