Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535010 | 0.87 | PTGS2 (0.54) | ALDH1A1HPGDMAPTL3MBTL1NPSR1 | |
| SCHEMBL9538398 | 0.85 | PTGS1 (0.55) | ALDH1A1HPGDMAPTAKR1C3AKR1C2 | |
| SCHEMBL28401357 | 0.81 | PTGS2 (0.52) | ALDH1A1MAPTKMT2ACYP2C9AKR1B1 | |
| SCHEMBL9539520 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTL3MBTL1KDM4E | |
| SCHEMBL28889111 | 0.79 | PTGS2 (0.55) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL8100934 | 0.78 | CA2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL9535435 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTNPSR1KDM4E | |
| SCHEMBL9624571 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1HPGDKDM4EAKR1C3AKR1C2 | |
| SCHEMBL9535213 | 0.76 | PTGS2 (0.56) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9536561 | 0.75 | MAPT (0.57) | ALDH1A1HPGDLMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| CN-1019388-B | Process for preparing N-alkylsulfonamide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | CN | disclosed |
| CN-88103277-A | Novel N-alkane sulfonyl aniline derivatives and preparation method thereof and the pharmaceutical composition that comprises this material | — | 1988-12-07 | — | — | CN | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |