Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535335 | 0.80 | MAPT (0.53) | L3MBTL1POLBMAPTALDH1A1LMNA | |
| SCHEMBL9535501 | 0.79 | MAPT (0.56) | L3MBTL1POLBMAPTALDH1A1LMNA | |
| SCHEMBL9537872 | 0.78 | HPGD (0.59) | L3MBTL1POLBMAPTALDH1A1LMNA | |
| SCHEMBL9538064 | 0.77 | ALDH1A1 (0.47) | POLBMAPTHTTAKR1C3AKR1C2 | |
| SCHEMBL9538031 | 0.77 | MAPT (0.50) | L3MBTL1POLBMAPTAKR1C3AKR1C2 | |
| SCHEMBL1341389 | 0.77 | ALDH1A1 (0.59) | MAPTHTTALDH1A1DHFRSMN1; SMN2 | |
| SCHEMBL9657052 | 0.75 | SMN1; SMN2 (0.50) | L3MBTL1HTTAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL220432 | 0.75 | LMNA (0.55) | L3MBTL1MAPTHTTALDH1A1LMNA | |
| SCHEMBL9535502 | 0.73 | MAPT (0.46) | L3MBTL1POLBMAPTALDH1A1 | |
| Hydrogen Peroxide SCHEMBL28640288 | 0.73 | CA1 (0.55) | POLBMAPTHTTDHFRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |