Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 4/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | PDE9A | O76083 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536812 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAAGLAL3MBTL1 | |
| SCHEMBL9536884 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EGAAGLAL3MBTL1 | |
| SCHEMBL9754547 | 0.78 | MCL1 (0.55) | ALDH1A1KDM4EGAAGLAL3MBTL1 | |
| SCHEMBL9701575 | 0.77 | MDM2 (0.59) | ALDH1A1KDM4EGAAGLAL3MBTL1 | |
| SCHEMBL4474609 | 0.77 | MDM2 (0.62) | ALDH1A1KDM4EGAAGLAL3MBTL1 | |
| SCHEMBL7339595 | 0.74 | KDM4E (0.52) | ALDH1A1KDM4EGAAPIM1MCL1 | |
| SCHEMBL9700724 | 0.74 | KDM4E (0.66) | ALDH1A1KDM4EGAAGLAL3MBTL1 | |
| SCHEMBL9529307 | 0.74 | KDM4E (0.55) | ALDH1A1KDM4EGAAGLAL3MBTL1 | |
| SCHEMBL7397061 | 0.72 | KDM4E (0.64) | ALDH1A1KDM4EGAAGLAL3MBTL1 | |
| SCHEMBL9525290 | 0.72 | KDM4E (0.64) | ALDH1A1KDM4EGAAGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |