Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539004 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPTKMT2AMEN1 | |
| SCHEMBL9535469 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1ATMMAPTKMT2A | |
| SCHEMBL9539498 | 0.75 | AKR1C3 (0.53) | ALDH1A1TDP1ATMMAPTKMT2A | |
| SCHEMBL4940492 | 0.72 | EPAS1 (0.56) | ALDH1A1TDP1ATMMAPTKMT2A | |
| SCHEMBL30615510 | 0.72 | EPAS1 (0.56) | ALDH1A1TDP1ATMMAPTKMT2A | |
| SCHEMBL9537323 | 0.71 | CASP6 (0.51) | ALDH1A1TDP1ATMMAPTKMT2A | |
| SCHEMBL9536353 | 0.71 | TDP1 (0.50) | ALDH1A1TDP1ATMMAPTKMT2A | |
| SCHEMBL9536018 | 0.71 | ALDH1A1 (0.54) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL9536533 | 0.71 | ALDH1A1 (0.47) | ALDH1A1TDP1ATMMAPTKMT2A | |
| SCHEMBL9535377 | 0.70 | LMNA (0.49) | ALDH1A1TDP1ATMMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |