Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571183 | 0.95 | KMT2A (0.42) | KMT2APOLBMEN1ALDH1A1HRH3 | |
| SCHEMBL3603694 | 0.89 | KMT2A (0.40) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL5451185 | 0.79 | KMT2A (0.39) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL9535573 | 0.75 | KMT2A (0.36) | KMT2APOLBALDH1A1 | |
| SCHEMBL5929382 | 0.72 | ALDH1A1 (0.37) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| Cga-271312 SCHEMBL6801995 | 0.70 | HRH3 (0.37) | KMT2APOLBMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9374014 | 0.70 | TP53 (0.38) | KMT2APOLBMEN1ALDH1A1CYP3A4 | |
| SCHEMBL9536702 | 0.69 | SMN1; SMN2 (0.39) | KMT2APOLBMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9482552 | 0.69 | BRD4 (0.37) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20015892 | 0.68 | CHRNB2 (0.51) | CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811374-A | INSECTICIDES; ACARICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-22 | — | — | US | disclosed |
| EP-0442077-B1 | 3-Aryl-pyrrolidine-2,4-dione derivatives as insecticides and herbicides | BAYER AG (DE) | 1995-11-08 | — | — | EP | disclosed |
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5142065-A | Intermediates for herbicides, fungicides, miticides and insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| US-5091537-A | Acylamino acid ester derivatives; insecticide, fungicide, herbicide, acaricide, and antimycotic agent | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| EP-0442077-A2 | 3-Aryl-pyrrolidine-2,4-dione derivatives as insecticides and herbicides | BAYER AG (DE) | 1991-08-21 | — | — | EP | disclosed |
| US-4985063-A | INSECTICIDES, MITICIDES, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |