Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3603694 | 0.88 | KMT2A (0.40) | KMT2AALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL8575944 | 0.79 | KMT2A (0.46) | KMT2AALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL5929382 | 0.77 | ALDH1A1 (0.37) | KMT2ARAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL8571183 | 0.75 | KMT2A (0.42) | KMT2AALDH1A1MEN1POLB | |
| SCHEMBL14411037 | 0.69 | KMT2A (0.35) | KMT2ARAB9AALDH1A1KDM4ECYP2C9 | |
| SCHEMBL14411028 | 0.66 | RAB9A (0.35) | KMT2ARAB9AALDH1A1GAAPOLB | |
| SCHEMBL5437164 | 0.66 | KMT2A (0.38) | KMT2ARAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL4459107 | 0.66 | HPGD (0.31) | KMT2AALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL14411036 | 0.65 | KMT2A (0.32) | KMT2A | |
| SCHEMBL9535573 | 0.64 | KMT2A (0.36) | KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225170-A1 | 2-Halo-6-Alkylphenyl-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | disclosed |
| EP-1682501-A2 | 2-HALOGEN-6-ALKYL-PHENYL SUBSTITUTED TETRAMIC ACID DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044791-A2 | 2-HALOGEN-6-ALKYL-PHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225170-A1 | 2-Halo-6-Alkylphenyl-Substituted Tetramic Acid Derivatives | DDT, HDHD5, TBCA | KMT2A 2835/4885RAB9A 1747/4885ALDH1A1 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.