Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | RHOC | P08134 | 1/20 | 0.37 |
| ▸ | RHOA | P61586 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536801 | 0.88 | POLB (0.39) | OPRK1 | |
| SCHEMBL9539291 | 0.86 | KMT2A (0.44) | TACR1MEN1KMT2ASMN1; SMN2OPRK1 | |
| SCHEMBL9727478 | 0.83 | ALDH1A1 (0.51) | CCR1RHOCRHOAMAPTSMN1; SMN2 | |
| SCHEMBL9538045 | 0.83 | DRD1 (0.48) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9535443 | 0.81 | KMT2A (0.43) | TACR1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9534996 | 0.80 | OPRK1 (0.40) | OPRK1 | |
| SCHEMBL9537325 | 0.78 | ACE (0.43) | CCR1RHOCRHOAKMT2ACYP2C19 | |
| SCHEMBL9537713 | 0.78 | KMT2A (0.55) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9535584 | 0.77 | SMN1; SMN2 (0.38) | KMT2ASMN1; SMN2 | |
| SCHEMBL9535862 | 0.77 | ALDH1A1 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |