Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538045 | 0.88 | DRD1 (0.48) | — | |
| SCHEMBL9535638 | 0.88 | TACR1 (0.39) | OPRK1 | |
| SCHEMBL9539327 | 0.85 | OPRK1 (0.42) | OPRK1OPRM1 | |
| SCHEMBL9537062 | 0.85 | ALDH1A1 (0.50) | — | |
| SCHEMBL9534996 | 0.84 | OPRK1 (0.40) | OPRK1OPRM1 | |
| SCHEMBL9535862 | 0.81 | ALDH1A1 (0.39) | OPRM1 | |
| SCHEMBL9727467 | 0.81 | ALDH1A1 (0.55) | POLBOPRK1 | |
| SCHEMBL9537713 | 0.81 | KMT2A (0.55) | POLB | |
| SCHEMBL9535584 | 0.80 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL9537518 | 0.77 | ALDH1A1 (0.36) | POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |