Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535687 | 1.00 | LMNA (0.40) | LMNAMEN1KMT2AAOC3MAPT | |
| SCHEMBL9537012 | 0.75 | GAA (0.40) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL480760 | 0.75 | LMNA (0.67) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9535401 | 0.75 | GAA (0.40) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL15332519 | 0.72 | AOC3 (0.42) | MEN1KMT2AAOC3MAPT | |
| SCHEMBL9534759 | 0.69 | THRB (0.39) | LMNAMEN1KMT2AAOC3MAPT | |
| SCHEMBL9534763 | 0.69 | THRB (0.39) | LMNAMEN1KMT2AAOC3MAPT | |
| SCHEMBL3791186 | 0.69 | ALDH1A1 (0.40) | LMNAMEN1KMT2AAOC3MAPT | |
| SCHEMBL1029816 | 0.67 | KMT2A (0.43) | LMNAMEN1KMT2AAOC3MAPT | |
| SCHEMBL474385 | 0.67 | KMT2A (0.49) | LMNAMEN1KMT2AAOC3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244352-B1 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4808618-A | ANTIALLERGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0244352-A2 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-11-04 | — | — | EP | disclosed |