Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479409 | 0.89 | CALM1 (0.44) | LMNAGAATSHRHTTTAAR1 | |
| SCHEMBL269952 | 0.71 | CALM1 (0.65) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL18970294 | 0.70 | SORT1 (0.40) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL27326 | 0.69 | CALM1 (0.71) | ABCC4LMNAGAATSHRPTGS1 | |
| Methane SCHEMBL9562367 | 0.67 | CALM1 (0.67) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL198432 | 0.66 | CALM1 (0.75) | ABCC4LMNAGAATSHRPTGS1 | |
| Tannin Pyrogallol SCHEMBL29187616 | 0.66 | CALM1 (0.75) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL3056752 | 0.66 | MAPT (0.39) | LMNAGAAHTTRAB9AALDH1A1 | |
| SCHEMBL21249537 | 0.66 | GRM2 (0.40) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL21249526 | 0.66 | GRM2 (0.40) | ABCC4LMNAGAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531382-A1 | N-SUBSTITUTED-1,2,4-TRIAZOLONE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1993-03-17 | — | — | EP | disclosed |