Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538256 | 0.87 | HDAC1 (0.49) | HDAC1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9535377 | 0.80 | LMNA (0.49) | MAPK14PARP1GAANPC1RAB9A | |
| SCHEMBL9539469 | 0.80 | PTGS2 (0.53) | MAPK14GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15638643 | 0.75 | ALDH1A1 (0.47) | HDAC1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29581577 | 0.73 | ALDH1A1 (0.47) | HDAC1MAPK14GAANPC1RAB9A | |
| SCHEMBL3606443 | 0.73 | ALDH1A1 (0.47) | HDAC1MAPK14GAANPC1RAB9A | |
| SCHEMBL9535914 | 0.72 | MAP2K1 (0.47) | HDAC1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1627106 | 0.71 | HDAC1 (0.63) | HDAC1PARP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14190740 | 0.71 | PRKCI (0.53) | HDAC1PARP1GAASMN1; SMN2HDAC2 | |
| SCHEMBL9656997 | 0.71 | BRD4 (0.47) | HDAC1MAPK14PARP1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| CN-1019388-B | Process for preparing N-alkylsulfonamide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | CN | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| CN-88103277-A | Novel N-alkane sulfonyl aniline derivatives and preparation method thereof and the pharmaceutical composition that comprises this material | — | 1988-12-07 | — | — | CN | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |