Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535128 | 0.86 | TAAR1 (0.42) | CTSK | |
| SCHEMBL9537132 | 0.86 | L3MBTL1 (0.44) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL18295858 | 0.80 | ADRB3 (0.34) | SIGMAR1L3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL9533718 | 0.79 | LTB4R (0.54) | L3MBTL1 | |
| SCHEMBL2733417 | 0.78 | TAAR1 (0.37) | L3MBTL1MAPTCTSK | |
| SCHEMBL9536343 | 0.78 | L3MBTL1 (0.45) | SIGMAR1L3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL1872003 | 0.77 | ALDH1A1 (0.35) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL3654575 | 0.77 | CTSS (0.36) | HRH3SIGMAR1L3MBTL1ESRRGHDAC3 | |
| SCHEMBL18295871 | 0.76 | CA14 (0.42) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6540918 | 0.75 | HDAC1 (0.51) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532693-A1 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |