Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9535191 | 0.99 | SLC6A9 (0.43) | SLC6A9LMNAALDH1A1HPGDTDP1 | |
| SCHEMBL9536406 | 0.89 | ALDH1A1 (0.37) | ALDH1A1HPGDTDP1KDM4ERECQL | |
| SCHEMBL9538894 | 0.88 | SLC6A9 (0.44) | SLC6A9LMNAALDH1A1HPGDTDP1 | |
| SCHEMBL9535132 | 0.84 | SLC6A9 (0.43) | SLC6A9LMNAALDH1A1HSD17B10ADORA2A | |
| SCHEMBL9537953 | 0.83 | KDM4E (0.46) | SLC6A9LMNAALDH1A1HPGDTDP1 | |
| SCHEMBL9538129 | 0.77 | GAA (0.51) | SLC6A9LMNAALDH1A1TDP1KDM4E | |
| SCHEMBL9537181 | 0.77 | SLC6A9 (0.49) | SLC6A9LMNAALDH1A1HPGDTDP1 | |
| SCHEMBL9535079 | 0.77 | TSHR (0.45) | LMNAALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL9564914 | 0.76 | CYP3A4 (0.47) | SLC6A9LMNAALDH1A1HPGDTDP1 | |
| SCHEMBL9536805 | 0.75 | SLC6A9 (0.51) | SLC6A9LMNAALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | claimed |