Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | PYGM | P11217 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | PLD2 | O14939 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10549281 | 0.89 | SLC6A9 (0.43) | SLC6A2SLC6A4SLC6A9PYGMMAPT | |
| SCHEMBL9537428 | 0.86 | SLC6A9 (0.46) | SLC6A2SLC6A4SLC6A9PYGMMAPT | |
| SCHEMBL9535185 | 0.85 | MAPT (0.49) | SLC6A2SLC6A4CCR3PYGMMAPT | |
| SCHEMBL9536186 | 0.84 | MAPT (0.56) | SLC6A2SLC6A4CCR3MAPTCHRM4 | |
| SCHEMBL9537145 | 0.82 | SLC6A9 (0.53) | SLC6A9MAPTMEN1KMT2A | |
| SCHEMBL9539084 | 0.81 | MEN1 (0.52) | CCR3SLC6A9MAPTALDH1A1MEN1 | |
| Oxalic Acid SCHEMBL9540591 | 0.80 | ALDH1A1 (0.53) | SLC6A2SLC6A4CCR3ALDH1A1NPC1 | |
| Oxalic Acid SCHEMBL9540585 | 0.80 | ALDH1A1 (0.53) | SLC6A2SLC6A4CCR3ALDH1A1NPC1 | |
| SCHEMBL9535122 | 0.80 | SLC6A9 (0.65) | SLC6A2SLC6A4SLC6A9MAPTALDH1A1 | |
| SCHEMBL9536165 | 0.79 | CCR3 (0.56) | SLC6A2SLC6A4CCR3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | disclosed |