Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 5/20 | 0.62 |
| ▸ | PRKCA | P17252 | 5/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.62 |
| ▸ | PRKCG | P05129 | 4/20 | 0.62 |
| ▸ | PRKCH | P24723 | 4/20 | 0.62 |
| ▸ | PRKCI | P41743 | 4/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.62 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.62 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.62 |
| ▸ | CDK9 | P50750 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619764 | 0.85 | CAMK2D (0.57) | PRKCACCNT1CDK9PIM1RPS6KB1 | |
| SCHEMBL25282614 | 0.81 | CAMK2D (0.57) | CCNT1CDK9PIM1RPS6KB1CAMK2D | |
| SCHEMBL8923158 | 0.81 | GSK3B (0.47) | PRKCBPRKCAPRKCECCNT1CDK9 | |
| Bisindolylmaleimide Ix SCHEMBL29370657 | 0.77 | PRKCA (1.00) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| Bisindolylmaleimide Ix SCHEMBL1567017 | 0.77 | PRKCA (1.00) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| SCHEMBL8653893 | 0.75 | MEN1 (0.45) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| SCHEMBL5583029 | 0.74 | MEN1 (0.72) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| Bisindolylmaleimide Ix SCHEMBL29381390 | 0.73 | MEN1 (1.00) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| Bisindolylmaleimide Ix SCHEMBL2491726 | 0.73 | MEN1 (1.00) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| SCHEMBL8166773 | 0.71 | MEN1 (0.68) | PRKCBPRKCAPRKCEPRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328026-B1 | SUBSTITUTED PYRROLES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-28 | — | — | EP | claimed |