Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.45 |
| ▸ | CDK9 | P50750 | 3/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | PRKACA | P17612 | 2/20 | 0.44 |
| ▸ | PRKACG | P22612 | 2/20 | 0.44 |
| ▸ | PRKACB | P22694 | 2/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25282614 | 0.89 | CAMK2D (0.57) | CCNT1CDK9CCNA2CDK2PIM1 | |
| SCHEMBL8619764 | 0.85 | CAMK2D (0.57) | CCNT1CDK9CCNA2CDK2PIM1 | |
| SCHEMBL9536683 | 0.81 | PRKCB (0.62) | GSK3BCCNT1CDK9CCNA2CDK2 | |
| SCHEMBL4565063 | 0.74 | MAPT (0.41) | GSK3BPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL4564847 | 0.73 | CCNB2 (0.51) | GSK3BCDK2PIM1PRKCAPRKACA | |
| SCHEMBL3139598 | 0.73 | GSK3B (0.78) | GSK3BCCNT1CDK9CDK2PIM1 | |
| SCHEMBL8466339 | 0.71 | CCNT1 (0.44) | GSK3BCCNT1CDK9CCNA2CDK2 | |
| SCHEMBL30358319 | 0.71 | GSK3B (0.46) | GSK3BCCNT1CDK9CCNA2CDK2 | |
| SCHEMBL8920187 | 0.71 | PRKCG (0.59) | GSK3BCCNT1CDK9CDK2PIM1 | |
| SCHEMBL29447190 | 0.70 | GSK3B (0.53) | GSK3BCCNT1CDK9CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672618-A | TREATING DIABETIC COMPLICATIONS | ELI LILLY AND COMPANY (US) | 1997-09-30 | — | — | US | disclosed |