Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 9/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534479 | 0.92 | SMN1; SMN2 (0.34) | SMN1; SMN2HIF1ACCR4PTGS2MEN1 | |
| SCHEMBL9536181 | 0.87 | CCR4 (0.42) | CCR4TSHR | |
| SCHEMBL8901312 | 0.83 | PTGS2 (0.34) | SMN1; SMN2HIF1ACCR4PTGS2MEN1 | |
| SCHEMBL9534730 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2HIF1ACCR4PTGS2TSHR | |
| SCHEMBL9642244 | 0.81 | SCN9A (0.34) | CCR4 | |
| SCHEMBL9537281 | 0.79 | CCR4 (0.42) | CCR4 | |
| SCHEMBL9512513 | 0.79 | TSHR (0.36) | SMN1; SMN2HIF1ACCR4PTGS2TSHR | |
| SCHEMBL910148 | 0.78 | TSHR (0.36) | PTGS2MEN1LMNAKMT2ATSHR | |
| SCHEMBL909656 | 0.78 | TSHR (0.36) | SMN1; SMN2PTGS2LMNATSHR | |
| SCHEMBL8335333 | 0.76 | TSHR (0.32) | PTGS2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343752-B1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DOWELANCO (US) | 1993-12-01 | — | — | EP | disclosed |
| US-5163995-A | For use with grassy crops and soybeans | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | disclosed |