Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727246 | 0.84 | FKBP1A (0.46) | MEN1KMT2A | |
| SCHEMBL9535560 | 0.81 | TSHR (0.38) | MEN1KMT2AOPRK1OPRM1 | |
| SCHEMBL9536573 | 0.81 | MEN1 (0.43) | MEN1KMT2AOPRK1OPRM1EPHX2 | |
| SCHEMBL9536216 | 0.81 | ALDH1A1 (0.38) | MEN1KMT2AOPRK1OPRM1 | |
| SCHEMBL9538119 | 0.79 | TSHR (0.36) | MEN1KMT2AOPRK1OPRM1 | |
| SCHEMBL9539327 | 0.79 | OPRK1 (0.42) | MEN1KMT2AOPRK1OPRM1SLC6A3 | |
| SCHEMBL9538662 | 0.79 | SMN1; SMN2 (0.41) | MEN1KMT2AOPRK1OPRM1 | |
| SCHEMBL9535087 | 0.78 | FKBP1A (0.39) | MEN1KMT2AOPRK1OPRM1 | |
| SCHEMBL9538257 | 0.77 | KMT2A (0.49) | MEN1KMT2AOPRK1OPRM1MAPT | |
| SCHEMBL9538148 | 0.77 | KMT2A (0.42) | MEN1KMT2AOPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |