Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9537334 | 0.95 | ENPP2 (0.44) | KCNH2ENPP2HPGDMAPTSLC6A9 | |
| Oxalic Acid SCHEMBL9537337 | 0.95 | ENPP2 (0.44) | KCNH2ENPP2HPGDMAPTSLC6A9 | |
| SCHEMBL9536807 | 0.90 | SSTR5 (0.50) | KCNH2MAPTSSTR5LMNAHTT | |
| SCHEMBL9537882 | 0.86 | SLC6A9 (0.41) | KCNH2SLC6A9SSTR5NR4A2CYP2D6 | |
| SCHEMBL9535415 | 0.85 | SLC6A9 (0.55) | ENPP2MAPTSLC6A9LMNAPOLB | |
| Oxalic Acid SCHEMBL9540168 | 0.85 | ENPP2 (0.44) | ENPP2HPGDMAPTSSTR5LMNA | |
| Oxalic Acid SCHEMBL9540171 | 0.85 | ENPP2 (0.44) | ENPP2HPGDMAPTSSTR5LMNA | |
| SCHEMBL9537733 | 0.85 | ENPP2 (0.44) | ENPP2HPGDMAPTSSTR5LMNA | |
| SCHEMBL9698322 | 0.84 | SSTR5 (0.59) | KCNH2MAPTSSTR5LMNAHTT | |
| SCHEMBL9538842 | 0.84 | SSTR5 (0.52) | ENPP2SSTR5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | claimed |