Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | HRH1 | P35367 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537449 | 0.84 | SSTR5 (0.52) | RAB9ACYP2D6HRH3 | |
| SCHEMBL10804293 | 0.81 | KCNH2 (0.47) | KCNH2RAB9ACYP2D6HRH1CHRM1 | |
| SCHEMBL10547773 | 0.80 | HTR1A (0.56) | KCNH2CYP2D6HRH1CHRM1HRH3 | |
| Oxalic Acid SCHEMBL9537077 | 0.76 | HRH1 (0.56) | KCNH2CYP2D6HRH1CHRM1HRH3 | |
| Oxalic Acid SCHEMBL9537074 | 0.76 | HRH1 (0.56) | KCNH2CYP2D6HRH1CHRM1HRH3 | |
| SCHEMBL9538842 | 0.76 | SSTR5 (0.52) | ENPP2RAB9ACYP2D6HRH3 | |
| SCHEMBL9537733 | 0.75 | ENPP2 (0.44) | ENPP2RAB9ACYP2D6HRH1 | |
| SCHEMBL9535904 | 0.75 | KCNH2 (0.54) | KCNH2ENPP2RAB9AHRH1CHRM1 | |
| SCHEMBL14507936 | 0.72 | HRH3 (0.52) | KCNH2HRH3 | |
| SCHEMBL9536543 | 0.72 | SSTR5 (0.66) | KCNH2RAB9ACYP2D6HRH1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | disclosed |
| US-4839374-A | TREATING ALLERGIES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1989-06-13 | — | — | US | disclosed |
| EP-0151826-A1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-08-21 | — | — | EP | disclosed |