Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059754 | 0.89 | FABP4 (0.49) | FABP4ALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL9059999 | 0.89 | SMN1; SMN2 (0.39) | ALDH1A1MAPTKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9311252 | 0.78 | FABP4 (0.49) | FABP4ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9059577 | 0.73 | ALDH1A1 (0.45) | FABP4ALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL9539853 | 0.72 | HTR7 (0.38) | FABP4ALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL9059653 | 0.71 | ALDH1A1 (0.49) | FABP4ALDH1A1MAPTKDM4ERAB9A | |
| Fumaric Acid SCHEMBL9311944 | 0.69 | ALDH1A1 (0.64) | FABP4ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9311982 | 0.69 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL366745 | 0.69 | FABP4 (0.62) | FABP4ALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL27534803 | 0.69 | FABP4 (0.62) | FABP4ALDH1A1MAPTKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |