Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 3/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257513 | 0.85 | THRB (0.50) | ALDH1A1LMNAUSP2NPSR1TP53 | |
| SCHEMBL9225707 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNANPSR1TP53MAPT | |
| SCHEMBL4106190 | 0.83 | NPSR1 (0.45) | ALDH1A1LMNANPSR1TP53MAPT | |
| SCHEMBL29427715 | 0.83 | NPSR1 (0.45) | ALDH1A1LMNANPSR1TP53MAPT | |
| SCHEMBL9219992 | 0.83 | SMN1; SMN2 (0.45) | ALDH1A1LMNANPSR1TP53MAPT | |
| SCHEMBL9227832 | 0.83 | NPSR1 (0.45) | ALDH1A1LMNANPSR1TP53MAPT | |
| SCHEMBL9225885 | 0.82 | UBE2M (0.51) | ALDH1A1NPSR1TP53UBE2MDCUN1D1 | |
| SCHEMBL9218431 | 0.81 | ALDH1A1 (0.41) | ALDH1A1NPSR1TP53POLBUBE2M | |
| SCHEMBL9222967 | 0.81 | ALDH1A1 (0.41) | ALDH1A1NPSR1TP53POLBUBE2M | |
| SCHEMBL9226752 | 0.78 | RAB9A (0.51) | ALDH1A1NPSR1TP53MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5170727-A | — | — | None | — | — | JP | disclosed |
| JP-H05170727-A | UREA DERIVATIVE | YAMANOUCHI PHARMACEUT CO LTD | 1993-07-09 | — | — | JP | disclosed |