Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754547 | 0.75 | MCL1 (0.55) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL9536884 | 0.74 | KDM4E (0.46) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL9535550 | 0.72 | ALDH1A1 (0.53) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL8123124 | 0.71 | IMPDH2 (0.38) | KDM4EALDH1A1CA1CA2MCL1 | |
| SCHEMBL4474609 | 0.71 | MDM2 (0.62) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL9536812 | 0.70 | ALDH1A1 (0.60) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL9538000 | 0.69 | NPC1 (0.44) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL9754436 | 0.69 | ALDH1A1 (0.33) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL9529006 | 0.69 | MDM2 (0.47) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL3836372 | 0.69 | KDM4E (0.50) | MDM2KDM4EALDH1A1GAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |