Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535284 | 0.80 | KDM4E (0.41) | KDM4E | |
| SCHEMBL9754365 | 0.79 | ALDH1A1 (0.36) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL9754463 | 0.76 | PTGER3 (0.39) | — | |
| SCHEMBL9251638 | 0.74 | PTGER3 (0.46) | — | |
| SCHEMBL9754431 | 0.74 | RAB9A (0.45) | ALDH1A1HSD17B10TDP1KDM4ENPC1 | |
| SCHEMBL9754374 | 0.73 | NPC1 (0.40) | ALDH1A1HSD17B10TDP1KDM4ENPC1 | |
| SCHEMBL9754399 | 0.72 | MAOB (0.36) | ALDH1A1HPGD | |
| SCHEMBL9754396 | 0.72 | ACVR1 (0.42) | ALDH1A1HSD17B10KDM4ENPC1HPGD | |
| SCHEMBL9538008 | 0.69 | MDM2 (0.42) | ALDH1A1PARP1HSD17B10KDM4ENPC1 | |
| SCHEMBL9248549 | 0.68 | GAA (0.39) | ALDH1A1PDE4BTDP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | claimed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |