Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665676 | 0.80 | TACR3 (0.43) | BLMRIPK1NPY5ROPRM1MMP9 | |
| SCHEMBL6888854 | 0.79 | TACR1 (0.46) | ADRB3 | |
| SCHEMBL9539144 | 0.73 | ENPP2 (0.45) | NPY5R | |
| SCHEMBL9539370 | 0.72 | ENPP2 (0.43) | NPY5R | |
| SCHEMBL7670805 | 0.71 | TACR1 (0.44) | ROCK2ROCK1NPY5RMMP9 | |
| SCHEMBL15645088 | 0.71 | CTSK (0.52) | — | |
| SCHEMBL22620869 | 0.71 | CTSK (0.52) | — | |
| SCHEMBL7095879 | 0.71 | CTSK (0.52) | — | |
| SCHEMBL10209784 | 0.71 | CTSK (0.52) | — | |
| SCHEMBL7670973 | 0.71 | NPY5R (0.46) | NPY5RADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |