Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539374 | 0.82 | TACR3 (0.45) | ENPP2NPY5RCTRCRENMMP2 | |
| SCHEMBL9539141 | 0.79 | ITGB3 (0.46) | ENPP2NPY5RLPAR1 | |
| SCHEMBL9539144 | 0.79 | ENPP2 (0.45) | ENPP2NPY5RRENLPAR1 | |
| SCHEMBL7670973 | 0.75 | NPY5R (0.46) | NPY5R | |
| SCHEMBL9539148 | 0.72 | BLM (0.37) | NPY5R | |
| SCHEMBL3119335 | 0.69 | PTPN1 (0.49) | CTSKRENMMP2MMP3 | |
| SCHEMBL30047061 | 0.68 | SIRT2 (0.58) | CTSK | |
| SCHEMBL29179927 | 0.68 | SIRT2 (0.58) | CTSK | |
| SCHEMBL14396102 | 0.68 | SIRT2 (0.58) | CTSK | |
| SCHEMBL29144124 | 0.67 | CTSL (0.58) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |