Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830505 | 0.79 | PDE7A (0.39) | PDE7ASLC6A2SLC6A4SLC6A3FBP1 | |
| SCHEMBL9536540 | 0.76 | PDE7A (0.55) | PDE7AFBP1KDM4EALDH1A1MAPT | |
| SCHEMBL9535611 | 0.74 | PTGS2 (0.56) | PDE7AGAAMAPTALOX15HSD17B10 | |
| SCHEMBL9537079 | 0.71 | MAPT (0.43) | PDE7AGAAALDH1A1MAPTALOX15 | |
| SCHEMBL7274539 | 0.70 | KMT2A (0.41) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL2318636 | 0.70 | USP2 (0.44) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL6264703 | 0.69 | PDE7A (0.43) | PDE7ASLC6A2SLC6A4SLC6A3FBP1 | |
| SCHEMBL11729689 | 0.67 | KCNH2 (0.46) | PDE7AFBP1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22636690 | 0.67 | ADORA2A (0.50) | GAAKDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL9535423 | 0.67 | ALDH1A1 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| CN-1019388-B | Process for preparing N-alkylsulfonamide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | CN | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| CN-88103277-A | Novel N-alkane sulfonyl aniline derivatives and preparation method thereof and the pharmaceutical composition that comprises this material | — | 1988-12-07 | — | — | CN | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |