Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3649899 | 0.81 | MCOLN3 (0.50) | L3MBTL1MAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10618531 | 0.80 | SMN1; SMN2 (0.38) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL23174837 | 0.77 | KAT6A (0.38) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL8713487 | 0.76 | HTR6 (0.53) | KDM4EALDH1A1SMN1; SMN2KMT2ATDP1 | |
| SCHEMBL21815478 | 0.75 | MEN1 (0.47) | NPC1RAB9AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9948959 | 0.75 | HTR6 (0.51) | KDM4EALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL28514735 | 0.73 | MRGPRX4 (0.45) | KDM4EL3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL8729004 | 0.73 | KDM4E (0.39) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL27559786 | 0.73 | ALDH1A1 (0.42) | RAB9AKDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11782542 | 0.73 | ALDH1A1 (0.49) | KDM4EL3MBTL1MAPTALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993004686-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-18 | — | — | WO | disclosed |