Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28715400 | 0.77 | ALDH1A1 (0.36) | KDM4EALDH1A1F2MAPTKMT2A | |
| SCHEMBL28695024 | 0.77 | TSHR (0.33) | ALDH1A1KMT2ATSHRHSD17B10MAPK1 | |
| SCHEMBL28704162 | 0.75 | PTGDR2 (0.42) | KMT2ATSHRHSD17B10SMN1; SMN2CASP1 | |
| SCHEMBL28467370 | 0.74 | TSHR (0.34) | ALDH1A1KMT2ATSHRHSD17B10MAPK1 | |
| SCHEMBL9539690 | 0.73 | NPC1 (0.43) | KDM4EALDH1A1F2MAPTKMT2A | |
| SCHEMBL11782542 | 0.73 | ALDH1A1 (0.49) | KDM4EALDH1A1F2MAPTKMT2A | |
| SCHEMBL3918082 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KMT2ATSHRMEN1LMNA | |
| SCHEMBL28823865 | 0.71 | RAPGEF4 (0.38) | KDM4EALDH1A1F2MAPTCA1 | |
| SCHEMBL2656782 | 0.71 | L3MBTL1 (0.42) | KDM4EALDH1A1F2MAPTCA1 | |
| SCHEMBL29282409 | 0.71 | PTGDR2 (0.36) | KMT2ATSHRHSD17B10MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839833-A2 | Catalyst systems for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA S.A. (ES) | 1998-05-06 | — | — | EP | disclosed |