Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573293 | 1.00 | APP (0.47) | APPSMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL9705589 | 0.93 | TRPA1 (0.43) | ALDH1A1TSHRTRPA1 | |
| SCHEMBL9828836 | 0.90 | LMNA (0.50) | APPSMN1; SMN2MAPK1KDM4EALDH1A1 | |
| SCHEMBL3097354 | 0.90 | KDM4E (0.50) | APPSMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL9541070 | 0.88 | THRA (0.45) | APPSMN1; SMN2MAPK1KDM4EALDH1A1 | |
| SCHEMBL9705573 | 0.86 | KCNA3 (0.50) | L3MBTL1 | |
| SCHEMBL9705568 | 0.84 | KCNA3 (0.48) | — | |
| SCHEMBL10614694 | 0.84 | KCNA3 (0.48) | — | |
| SCHEMBL4086993 | 0.84 | TRPA1 (0.40) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL9539656 | 0.84 | KCNA3 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228803-B1 | IONENE ELASTOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-09-16 | — | — | EP | claimed |
| US-4677182-A | COATINGS, ADHESIVES | MINNESOTA MINING AND MANUFACTURING CO. (US) | 1987-06-30 | — | — | US | claimed |
| WO-1993005028-A1 | RECEPTOR COMPOUNDS BASED ON 1,7-DIOXA-4,10-DIAZACYCLODODECANE | SCIMAT LIMITED (GB) | 1993-03-18 | — | — | WO | disclosed |
| EP-0228803-B1 | IONENE ELASTOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-09-16 | — | — | EP | disclosed |
| US-4794031-A | POLYMERIC DIAMINES, DIHALIDE LINKING AGENTS, POLYETHERS, ACRYLIC COPOLYMERS, ENCAPPING | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-12-27 | — | — | US | disclosed |
| US-4734458-A | QUATERNIZED POLYAMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0228803-A2 | Ionene elastomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-07-15 | — | — | EP | disclosed |
| US-4677182-A | COATINGS, ADHESIVES | MINNESOTA MINING AND MANUFACTURING CO. (US) | 1987-06-30 | — | — | US | disclosed |