Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.50 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828891 | 0.91 | LMNA (0.45) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL9539720 | 0.90 | APP (0.47) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL1573293 | 0.90 | APP (0.47) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL4122924 | 0.88 | L3MBTL1 (0.53) | LMNAMEN1ALDH1A1MAPK1KMT2A | |
| SCHEMBL9541070 | 0.87 | THRA (0.45) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL3097354 | 0.85 | KDM4E (0.50) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL23267301 | 0.85 | LMNA (0.53) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL2697362 | 0.85 | LMNA (0.53) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL4487824 | 0.84 | LTA4H (0.53) | CYP3A4SMN1; SMN2KDM4ETSHRLTA4H | |
| SCHEMBL9705589 | 0.84 | TRPA1 (0.43) | ALDH1A1TSHRLTA4HHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199281-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND INSECTICIDAL, ACARICIDAL, NEMATICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4837217-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0199281-A2 | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |