Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400124 | 0.80 | LMNA (0.34) | LMNAHTTATMALDH1A1CYP1A2 | |
| SCHEMBL9539862 | 0.77 | ALDH1A1 (0.35) | LMNAHTTATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL10400122 | 0.77 | TAS1R3 (0.34) | LMNAHTTATMHPGDSMN1; SMN2 | |
| SCHEMBL10458605 | 0.77 | KMT2A (0.40) | LMNAHTTATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL9539481 | 0.74 | KMT2A (0.37) | LMNAHTTATMMAPTMEN1 | |
| SCHEMBL9818604 | 0.73 | NPC1 (0.43) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL10400826 | 0.73 | F2 (0.34) | LMNAHTTATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL29006882 | 0.71 | PLAU (0.46) | LMNAALDH1A1MAPTCYP1A2MEN1 | |
| SCHEMBL28424914 | 0.70 | HSD17B10 (0.51) | LMNASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL9818596 | 0.69 | MEN1 (0.36) | HTTSMN1; SMN2ALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337944-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |