Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132941 | 0.79 | SSTR4 (0.34) | HPGDHTT | |
| SCHEMBL3873605 | 0.71 | HPGD (0.32) | HPGD | |
| SCHEMBL23485288 | 0.67 | HPGD (0.50) | HPGDRIPK1HTTMEN1KMT2A | |
| SCHEMBL7089700 | 0.64 | KMT2A (0.58) | RIPK1HTTMEN1CYP3A4CYP2C9 | |
| SCHEMBL30064 | 0.64 | ACHE (0.42) | HPGDHTTL3MBTL1 | |
| SCHEMBL20671261 | 0.63 | ALDH1A1 (0.38) | — | |
| SCHEMBL26054600 | 0.62 | CES2 (0.34) | HPGDRIPK1HTTMEN1KMT2A | |
| SCHEMBL20671370 | 0.60 | ACHE (0.46) | — | |
| SCHEMBL1578922 | 0.60 | HPGD (0.46) | HPGDHTTCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL23032197 | 0.59 | CYP3A4 (0.43) | HPGDMEN1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |