Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920848 | 0.91 | CYP2C19 (0.47) | CYP2C19CCKBR | |
| SCHEMBL9540219 | 0.89 | CCKBR (0.47) | CYP2C19CCKBR | |
| SCHEMBL9541664 | 0.89 | CCKBR (0.48) | CYP2C19CCKBR | |
| SCHEMBL8922081 | 0.89 | CYP2C19 (0.43) | CYP2C19KCNN4CCKBR | |
| SCHEMBL9544115 | 0.87 | CYP2C19 (0.46) | CYP2C19KCNN4 | |
| SCHEMBL8919504 | 0.84 | CCKBR (0.56) | CCKBR | |
| SCHEMBL9542930 | 0.84 | SLC6A2 (0.45) | CYP2C19 | |
| SCHEMBL9541670 | 0.81 | CCKBR (0.51) | CYP2C19CCKBR | |
| SCHEMBL9366810 | 0.79 | CYP2C19 (0.47) | CYP2C19CCKBR | |
| SCHEMBL9544058 | 0.78 | CCKBR (0.47) | CYP2C19CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015059-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1993-08-05 | — | — | WO | disclosed |