Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924340 | 0.88 | CYP2C19 (0.46) | CYP2C19KDM1AKDM1BKCNN4RAB9A | |
| SCHEMBL9540184 | 0.87 | CYP2C19 (0.43) | CYP2C19KCNN4 | |
| SCHEMBL8920848 | 0.86 | CYP2C19 (0.47) | CYP2C19RAB9A | |
| SCHEMBL8921951 | 0.85 | CCKBR (0.51) | GAA | |
| SCHEMBL9541664 | 0.82 | CCKBR (0.48) | CYP2C19 | |
| SCHEMBL9540219 | 0.82 | CCKBR (0.47) | CYP2C19 | |
| SCHEMBL9542930 | 0.80 | SLC6A2 (0.45) | CYP2C19 | |
| SCHEMBL9541670 | 0.80 | CCKBR (0.51) | CYP2C19 | |
| SCHEMBL8398551 | 0.78 | CYP2C19 (0.41) | CYP2C19AADATTSHR | |
| SCHEMBL9542893 | 0.76 | CCKBR (0.44) | CYP2C19RAB9AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015059-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1993-08-05 | — | — | WO | disclosed |