Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16306324 | 0.69 | GAA (0.41) | MAPT | |
| SCHEMBL11032087 | 0.69 | HRH4 (0.38) | LMNASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL9540291 | 0.67 | HRH4 (0.38) | LMNASMN1; SMN2ALDH1A1KDM4ENLRP3 | |
| SCHEMBL4788944 | 0.64 | KCNH3 (0.38) | S1PR2LMNASMN1; SMN2NPSR1ELANE | |
| SCHEMBL8897910 | 0.63 | KCNH3 (0.37) | S1PR2LMNASMN1; SMN2NPSR1ELANE | |
| SCHEMBL12595626 | 0.61 | GAA (0.36) | MAPT | |
| SCHEMBL1724131 | 0.61 | L3MBTL1 (0.51) | S1PR2LMNASMN1; SMN2NPSR1KCNH3 | |
| SCHEMBL96273 | 0.60 | ALDH1A1 (0.70) | S1PR2LMNASMN1; SMN2NPSR1KCNH3 | |
| SCHEMBL8535750 | 0.60 | L3MBTL1 (0.54) | S1PR2LMNASMN1; SMN2NPSR1KCNH3 | |
| SCHEMBL30174089 | 0.60 | L3MBTL1 (0.54) | S1PR2LMNASMN1; SMN2NPSR1KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993002707-A1 | NEW ANTI-DIARRHEIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1993-02-18 | — | — | WO | claimed |
| WO-1993002707-A1 | NEW ANTI-DIARRHEIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1993-02-18 | — | — | WO | disclosed |
| EP-0066303-A1 | 2-Azidomethyl-1,4-benzodiazepines, their salts, process for preparing them and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1982-12-08 | — | — | EP | disclosed |