Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541838 | 0.86 | IDO1 (0.44) | FBP1NFE2L2MEN1KMT2ANPC1 | |
| SCHEMBL9539528 | 0.80 | ALDH1A1 (0.48) | FBP1NPC1RAB9AMAOBTSHR | |
| SCHEMBL7435417 | 0.76 | NFE2L2 (0.53) | FBP1NFE2L2MEN1KMT2ANPC1 | |
| SCHEMBL3904046 | 0.76 | NFE2L2 (0.73) | FBP1NFE2L2MEN1KMT2ANPC1 | |
| SCHEMBL5496405 | 0.76 | NFE2L2 (0.73) | FBP1NFE2L2MEN1KMT2ANPC1 | |
| SCHEMBL1132385 | 0.74 | ALDH1A1 (0.39) | FBP1NFE2L2MEN1KMT2AMAPT | |
| SCHEMBL9538889 | 0.73 | NPBWR1 (0.40) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL3237563 | 0.73 | NFE2L2 (0.58) | FBP1NFE2L2MEN1KMT2ANPC1 | |
| SCHEMBL11708990 | 0.73 | APP (0.42) | NFE2L2MEN1KMT2AMAPTMAOB | |
| SCHEMBL9538666 | 0.72 | NPBWR1 (0.39) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311955-B1 | BICYCLIC PEROXIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |
| US-5134240-A | Malaria therapy | HOFFMANN-LAROCHE, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0311955-A2 | Bicyclic peroxide | F. HOFFMANN-LA ROCHE AG (CH) | 1989-04-19 | — | — | EP | disclosed |