SCHEMBL9818059

SCHEMBL9818059

O=Cc1cccc(Oc2ccc(Cl)cc2)n1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TERT O14746 7/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HAO1 Q9UJM8 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
ST14 Q9Y5Y6 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
SCN9A Q15858 1/20 0.37
P2RX3 P56373 2/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9540409 0.84 LMNA (0.43) TERTMEN1KMT2AHTTL3MBTL1
SCHEMBL11152339 0.84 MAP4K4 (0.49) TERTL3MBTL1F2F10
SCHEMBL11149465 0.83 KDM4E (0.50) TERTMEN1KMT2AHTTL3MBTL1
SCHEMBL9785577 0.83 L3MBTL1 (0.44) MEN1KMT2AHTTL3MBTL1HAO1
SCHEMBL10708134 0.83 L3MBTL1 (0.50) TERTMEN1KMT2AHTTL3MBTL1
SCHEMBL10988595 0.83 TERT (0.52) TERTMEN1KMT2AHTTL3MBTL1
SCHEMBL10547233 0.80 L3MBTL1 (0.41) MEN1KMT2AHTTL3MBTL1HAO1
SCHEMBL10547338 0.80 L3MBTL1 (0.41) MEN1KMT2AHTTL3MBTL1HAO1
SCHEMBL10977276 0.80 DRD1 (0.45) TERTMEN1KMT2AHTTL3MBTL1
SCHEMBL9853478 0.80 TERT (0.46) TERTMEN1KMT2AHTTF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0060838-A4 CERTAIN 6-CHLORO-2-DI-(SUBSTITUTED PHENOXY) METHYL PYRIDINES. DOW CHEMICAL CO (US) 1983-03-23 EP claimed
US-4358594-A Process for preparing certain 6-phenoxy-2-pyridinecarboxaldehydes THE DOW CHEMICAL CO. (US) 1982-11-09 US claimed
EP-0060838-A1 CERTAIN 6-CHLORO-2-DI-(SUBSTITUTED PHENOXY) METHYL PYRIDINES THE DOW CHEMICAL COMPANY (US) 1982-09-29 EP claimed
WO-1982001003-A1 CERTAIN 6-CHLORO-2-DI-(SUBSTITUTED PHENOXY)METHYL PYRIDINES MALHOTRA S 1982-04-01 WO claimed
US-4281133-A INSECTICIDES THE DOW CHEMICAL COMPANY (US) 1981-07-28 US claimed
EP-0298590-B1 HALOGENATED ESTERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-12-11 EP disclosed
EP-0298590-A1 Halogenated esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-01-11 EP disclosed