SCHEMBL9540557

SCHEMBL9540557

C[N+](CCNC(=O)c1ccccc1)(Cc1ccccc1)Cc1ccc2ccccc2c1.N#CNC#N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.42
CTSB P07858 2/20 0.42
CTSS P25774 2/20 0.42
CTSK P43235 1/20 0.42
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
TMEM97 Q5BJF2 2/20 0.41
SIGMAR1 Q99720 2/20 0.41
OPRM1 P35372 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
ALOX5 P09917 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
MCHR1 Q99705 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyanamide SCHEMBL9538981 0.77 NQO2 (0.41) CTSLCTSBCTSSCTSKHDAC3
Hydrochloric Acid SCHEMBL9539057 0.73 RAB9A (0.54) HDAC2HDAC8HDAC6NPC1RAB9A
SCHEMBL5969148 0.71 ESRRG (0.60) HDAC3HDAC1HDAC2NR1H4HDAC4
Hydrochloric Acid SCHEMBL5683129 0.71 RAB9A (0.46) HDAC2HDAC8HDAC6NPC1RAB9A
SCHEMBL27920877 0.69 NR1H4 (0.70) HDAC3HDAC1HDAC2NR1H4HDAC4
SCHEMBL9539316 0.68 NPC1 (0.40) HDAC3HDAC1HDAC2TMEM97SIGMAR1
SCHEMBL15071554 0.67 LMNA (0.61) HDAC3HDAC1HDAC2HDAC4HDAC7
SCHEMBL3231717 0.66 KMT2A (0.65) NPC1RAB9ANQO2MTNR1AMTNR1B
SCHEMBL3240913 0.65 NPC1 (0.69) HDAC3HDAC1HDAC2ALOX5HDAC4
Hydrochloric Acid SCHEMBL9538582 0.64 RAB9A (0.53) HDAC2HDAC8HDAC6NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993002042-A1 AMIDE-CONTAINING QUATERNARY AMMONIUM SALTS EASTMAN KODAK COMPANY (US) 1993-02-04 WO claimed
WO-1993002042-A1 AMIDE-CONTAINING QUATERNARY AMMONIUM SALTS EASTMAN KODAK COMPANY (US) 1993-02-04 WO disclosed