Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540491 | 0.83 | BCHE (0.49) | SMN1; SMN2BCHEACHEMEN1KMT2A | |
| SCHEMBL9539244 | 0.83 | NPC1 (0.52) | RAB9ANPC1LMNAPOLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9538582 | 0.81 | RAB9A (0.53) | RAB9ANPC1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL15071554 | 0.80 | LMNA (0.61) | RAB9ANPC1LMNAPOLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5683129 | 0.80 | RAB9A (0.46) | RAB9ANPC1LMNAPOLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28671813 | 0.79 | TGM2 (0.48) | RAB9ANPC1POLBSMN1; SMN2BCHE | |
| Hydrochloric Acid SCHEMBL4884176 | 0.79 | BCHE (0.53) | RAB9ANPC1SMN1; SMN2BCHEACHE | |
| SCHEMBL17083922 | 0.78 | TGM2 (0.49) | RAB9ANPC1POLBSMN1; SMN2BCHE | |
| SCHEMBL31476923 | 0.78 | BCHE (0.51) | RAB9ANPC1SMN1; SMN2BCHEACHE | |
| SCHEMBL20598039 | 0.77 | TAAR1 (0.48) | RAB9ANPC1LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993002042-A1 | AMIDE-CONTAINING QUATERNARY AMMONIUM SALTS | EASTMAN KODAK COMPANY (US) | 1993-02-04 | — | — | WO | claimed |
| WO-1993002399-A1 | TONERS AND DEVELOPERS CONTAINING AMIDE-CONTAINING QUATERNARY AMMONIUM SALTS AS CHARGE CONTROL AGENTS | EASTMAN KODAK COMPANY (US) | 1993-02-04 | — | — | WO | claimed |
| US-5162188-A | Toners and developers containing amide-containing quaternary ammonium salts as charge control agents | EASTMAN KODAK COMPANY (US) | 1992-11-10 | — | — | US | claimed |
| WO-1993002399-A1 | TONERS AND DEVELOPERS CONTAINING AMIDE-CONTAINING QUATERNARY AMMONIUM SALTS AS CHARGE CONTROL AGENTS | EASTMAN KODAK COMPANY (US) | 1993-02-04 | — | — | WO | disclosed |
| WO-1993002042-A1 | AMIDE-CONTAINING QUATERNARY AMMONIUM SALTS | EASTMAN KODAK COMPANY (US) | 1993-02-04 | — | — | WO | disclosed |
| US-5162188-A | Toners and developers containing amide-containing quaternary ammonium salts as charge control agents | EASTMAN KODAK COMPANY (US) | 1992-11-10 | — | — | US | disclosed |