Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 8/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 2/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568868 | 0.93 | HRH3 (0.49) | HRH3LCKKDRSRCESR1 | |
| Hydrochloric Acid SCHEMBL8561027 | 0.91 | HRH3 (0.48) | HRH3LCKKDRSRCESR1 | |
| SCHEMBL8561272 | 0.86 | GAK (0.37) | LCKSRCABL1RIPK2ACVR1 | |
| Hydrochloric Acid SCHEMBL8560744 | 0.85 | GAK (0.36) | LCKKDRSRCABL1RIPK2 | |
| SCHEMBL8567323 | 0.79 | MAPKAPK2 (0.46) | LCKKDRRIPK2 | |
| SCHEMBL8559967 | 0.78 | PDGFRA (0.48) | LCKSRCABL1RIPK2ACVR1 | |
| Water SCHEMBL8328226 | 0.77 | PDGFRA (0.47) | LCKRIPK2 | |
| Hydrochloric Acid SCHEMBL8566059 | 0.77 | HTT (0.50) | LCKRIPK2 | |
| SCHEMBL8566892 | 0.76 | POLB (0.39) | LCKSRCABL1RIPK2ACVR1 | |
| SCHEMBL8560347 | 0.76 | ERBB2 (0.52) | KDRRIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013097-A1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |