Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 6/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541268 | 0.72 | GPR17 (0.41) | GPR17CTDSP1FFAR1FFAR4 | |
| SCHEMBL9541379 | 0.70 | GPR17 (0.41) | GPR17CTDSP1FFAR1FFAR4PDE3B | |
| SCHEMBL9186131 | 0.69 | GPR17 (1.00) | GPR17 | |
| SCHEMBL9539867 | 0.68 | ALOX5 (0.46) | PDE3BPDE3A | |
| SCHEMBL2944735 | 0.67 | MTNR1A (0.66) | GPR17EGFR | |
| SCHEMBL5455 | 0.67 | FFAR1 (0.71) | FFAR1FFAR4 | |
| SCHEMBL7539349 | 0.66 | GPR17 (0.56) | GPR17PDE5APDE9AFFAR1EGFR | |
| SCHEMBL18509470 | 0.66 | APEX1 (0.59) | GPR17FFAR1EGFR | |
| SCHEMBL15463450 | 0.66 | GPR17 (0.66) | GPR17PDE5APDE9AEGFR | |
| Hydrochloric Acid SCHEMBL6440989 | 0.65 | FFAR1 (0.69) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |