Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541379 | 0.77 | GPR17 (0.41) | GPR17CTDSP1EGLN1FFAR1FFAR4 | |
| SCHEMBL9540970 | 0.72 | GPR17 (0.52) | GPR17CTDSP1FFAR1FFAR4 | |
| SCHEMBL25371544 | 0.62 | MAPK8 (0.67) | MAPK8 | |
| SCHEMBL5455 | 0.61 | FFAR1 (0.71) | FFAR1FFAR4ALDH1A1HSD17B10MAPT | |
| SCHEMBL8878029 | 0.61 | PTGS2 (0.62) | — | |
| Hydrochloric Acid SCHEMBL6440989 | 0.60 | FFAR1 (0.69) | FFAR1FFAR4ALDH1A1HSD17B10MAPT | |
| SCHEMBL20120068 | 0.60 | EGLN1 (0.52) | GPR17CTDSP1EGLN1ALDH1A1KDM4E | |
| SCHEMBL18509730 | 0.60 | PLA2G4A (0.47) | GPR17EGLN1MAPTSRC | |
| SCHEMBL29001054 | 0.59 | MAPT (0.46) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL9186131 | 0.59 | GPR17 (1.00) | GPR17ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |