Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | TDO2 | P48775 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29080074 | 0.76 | IDO1 (0.64) | GAAIDO1TDO2 | |
| SCHEMBL1126800 | 0.76 | RGS12 (0.48) | TSHRRGS12 | |
| SCHEMBL12879744 | 0.76 | MEN1 (0.48) | ALDH1A1GAANAAATSHRCPB1 | |
| SCHEMBL13964643 | 0.76 | IDO1 (0.51) | ALDH1A1IDO1TDO2TSHRCTSK | |
| SCHEMBL10547941 | 0.75 | NAAA (0.55) | NAAACTSKCTSBCTSSCTSL | |
| SCHEMBL8189814 | 0.75 | ALDH1A1 (0.52) | ALDH1A1GAANAAACTSKCTSB | |
| SCHEMBL10414305 | 0.75 | NAAA (0.55) | NAAACTSKCTSBCTSSCTSL | |
| SCHEMBL10414304 | 0.75 | NAAA (0.55) | NAAACTSKCTSBCTSSCTSL | |
| SCHEMBL8189821 | 0.75 | ALDH1A1 (0.52) | ALDH1A1GAANAAACTSKCTSB | |
| SCHEMBL10785543 | 0.75 | NAAA (0.55) | NAAACTSKCTSBCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013092-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | SARGES REINHARD (US) | 1993-07-08 | — | — | WO | disclosed |
| US-5011840-A | Imidazolidinedione derivatives in diabetes treatment | PFIZER INC. (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0269355-B1 | IMIDAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0269355-A1 | Imidazolidinedione derivatives | PFIZER INC. (US) | 1988-06-01 | — | — | EP | disclosed |