Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362772 | 0.91 | HSD11B1 (0.36) | LMNASMN1; SMN2ALDH1A1MAPTCCKAR | |
| SCHEMBL9362054 | 0.90 | ALDH1A1 (0.45) | LMNASMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL8921847 | 0.88 | LMNA (0.34) | LMNASMN1; SMN2RAB9ANPSR1CCR1 | |
| SCHEMBL9365841 | 0.86 | NPSR1 (0.32) | SMN1; SMN2ALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL8922451 | 0.86 | LMNA (0.38) | LMNASMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL8924472 | 0.84 | L3MBTL1 (0.33) | ALDH1A1MAPTNPSR1CCR1CCR2 | |
| SCHEMBL9362920 | 0.83 | LMNA (0.37) | LMNASMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL8919489 | 0.82 | L3MBTL1 (0.37) | SMN1; SMN2ALDH1A1MAPTCCKBRTSHR | |
| SCHEMBL8919162 | 0.81 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1MAPTCCKARCCKBR | |
| SCHEMBL8926039 | 0.79 | DRD2 (0.32) | LMNASMN1; SMN2RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015059-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1993-08-05 | — | — | WO | claimed |