Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541768 | 0.89 | ALDH1A1 (0.42) | THRBMAPTTP53ALDH1A1MEN1 | |
| SCHEMBL9540839 | 0.88 | TP53 (0.41) | THRBMAPTTP53ALDH1A1MEN1 | |
| SCHEMBL9541760 | 0.86 | TUBB4A (0.51) | THRBMAPTMEN1KMT2ATUBB4A | |
| SCHEMBL9542171 | 0.84 | GAA (0.46) | THRBMAPTTP53MEN1KMT2A | |
| SCHEMBL9584306 | 0.83 | SLC6A9 (0.44) | THRBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9542307 | 0.83 | MEN1 (0.42) | THRBMAPTTP53ALDH1A1MEN1 | |
| SCHEMBL9544575 | 0.83 | SLC6A9 (0.39) | THRBMAPTTP53ALDH1A1MEN1 | |
| SCHEMBL9542205 | 0.81 | TSHR (0.43) | MAPTTP53MEN1KMT2ATUBB4A | |
| SCHEMBL10453097 | 0.79 | SLC6A9 (0.51) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9542195 | 0.79 | MEN1 (0.40) | ALDH1A1MEN1KMT2ATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | claimed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | claimed |
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |