Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540800 | 0.87 | ALOX15 (0.47) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9540786 | 0.86 | ALOX15 (0.45) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9542144 | 0.76 | LMNA (0.48) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9543513 | 0.75 | HIF1A (0.43) | ALOX15TSHRMAPTNPC1RAB9A | |
| SCHEMBL9542158 | 0.75 | MEN1 (0.49) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL10455127 | 0.74 | LMNA (0.60) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9542288 | 0.73 | MEN1 (0.47) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9541759 | 0.73 | CA2 (0.51) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL8361113 | 0.73 | LMNA (0.77) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9542307 | 0.72 | MEN1 (0.42) | MEN1KMT2AALOX15TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |